Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908768 | 0.81 | TAS1R3 (0.43) | ALDH1A1LMNAALBMAPK1TAS1R3 | |
| SCHEMBL22219806 | 0.81 | TAS1R3 (0.54) | ALDH1A1LMNAALBMAPK1TAS1R3 | |
| SCHEMBL14628598 | 0.80 | HIF1A (0.60) | LMNA | |
| SCHEMBL13058825 | 0.80 | HIF1A (0.60) | LMNA | |
| SCHEMBL21423035 | 0.80 | HIF1A (0.60) | LMNA | |
| SCHEMBL18519494 | 0.79 | ALDH1A1 (0.62) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL24258545 | 0.79 | TAS1R3 (0.51) | TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL21263875 | 0.79 | TAS1R3 (0.48) | LMNATAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL20908479 | 0.78 | TAS1R3 (0.48) | TAS1R3TAS1R1P2RX3P2RX2 | |
| Didanosine SCHEMBL29387997 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |