Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908479 | 0.87 | TAS1R3 (0.48) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL15629327 | 0.82 | TAS1R3 (0.48) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL21423035 | 0.80 | HIF1A (0.60) | HIF1A | |
| SCHEMBL19666769 | 0.80 | HIF1A (0.60) | HIF1A | |
| SCHEMBL14628598 | 0.80 | HIF1A (0.60) | HIF1A | |
| SCHEMBL13058825 | 0.80 | HIF1A (0.60) | HIF1A | |
| SCHEMBL20908480 | 0.79 | ALDH1A1 (0.58) | TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL29642159 | 0.79 | TAS1R3 (0.70) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL24919980 | 0.79 | TAS1R3 (0.70) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL98800 | 0.77 | SLC29A1 (0.56) | SLC29A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752516-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-02-23 | — | — | EP | disclosed |