Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908944 | 0.91 | LMNA (0.53) | GAALMNAKDM4ETDP1HTT | |
| SCHEMBL22353526 | 0.89 | GAA (0.46) | GAALMNAKDM4ETDP1HTT | |
| SCHEMBL797884 | 0.84 | GAA (0.47) | GAALMNAKDM4ETDP1HTT | |
| SCHEMBL797883 | 0.84 | GAA (0.47) | GAALMNAKDM4ETDP1HTT | |
| SCHEMBL31039207 | 0.76 | PDE2A (0.53) | GAALMNAKDM4EALDH1A1PDE2A | |
| SCHEMBL20908819 | 0.76 | CNR2 (0.51) | CYP2A13NPC1RAB9ASMN1; SMN2PDE2A | |
| SCHEMBL26604074 | 0.75 | GAA (0.45) | GAALMNAKDM4ETDP1HTT | |
| SCHEMBL23617925 | 0.73 | SIGMAR1 (0.49) | TDP1PDE2APDE3AKMT2AMEN1 | |
| SCHEMBL12383 | 0.73 | ALDH1A1 (0.55) | GAALMNAKDM4ETDP1HTT | |
| SCHEMBL27238707 | 0.72 | ATM (0.48) | GAALMNAKDM4ETDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3696176-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2022-05-04 | — | — | EP | disclosed |
| WO-2019074275-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 대웅제약 | 2019-04-18 | — | — | WO | disclosed |