Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10193126 | 0.87 | GRM4 (0.35) | GRM4AAK1SORT1KDM4ELMNA | |
| SCHEMBL171691 | 0.84 | ADRB1 (0.43) | GRM4SORT1KDM4EADRB1 | |
| SCHEMBL803084 | 0.82 | SYK (0.39) | GRM4AAK1KDM4ELMNAALDH1A1 | |
| SCHEMBL28173201 | 0.81 | SORT1 (0.36) | GRM4AAK1SORT1KDM4ELMNA | |
| SCHEMBL31543495 | 0.78 | GABRA1 (0.39) | ADRB1 | |
| SCHEMBL1661164 | 0.78 | GABRA1 (0.39) | ADRB1 | |
| SCHEMBL20031180 | 0.78 | GRM4 (0.35) | GRM4AAK1KDM4ELMNAALDH1A1 | |
| SCHEMBL28203328 | 0.78 | HCRTR1 (0.35) | GRM4AAK1KDM4ELMNA | |
| SCHEMBL22795813 | 0.78 | AAK1 (0.33) | GRM4AAK1SORT1KDM4ELMNA | |
| SCHEMBL27269565 | 0.77 | ADORA2A (0.33) | ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310089-A1 | NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |