Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171691 | 0.83 | ADRB1 (0.43) | SORT1GRM4KDM4EADRB1 | |
| SCHEMBL20909663 | 0.81 | GRM4 (0.35) | SORT1AAK1GRM4KDM4ELMNA | |
| SCHEMBL10193126 | 0.81 | GRM4 (0.35) | SORT1AAK1GRM4KDM4ELMNA | |
| SCHEMBL22795813 | 0.76 | AAK1 (0.33) | SORT1AAK1GRM4KDM4ELMNA | |
| SCHEMBL803084 | 0.76 | SYK (0.39) | AAK1GRM4KDM4ELMNAALDH1A1 | |
| SCHEMBL8751966 | 0.75 | TRPV4 (0.33) | ADRB1 | |
| SCHEMBL2014949 | 0.75 | GABRA1 (0.38) | ADRB1 | |
| SCHEMBL18581 | 0.75 | LMNA (0.38) | KDM4ELMNAALDH1A1POLB | |
| SCHEMBL25469619 | 0.74 | GRM4 (0.36) | GRM4KDM4ELMNAALDH1A1POLB | |
| SCHEMBL28203328 | 0.72 | HCRTR1 (0.35) | AAK1GRM4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207506-A | Condensed heterocyclic compouds and noxious organism control agent | 日产化学工业株式会社 | 2017-09-26 | — | — | CN | disclosed |