Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684275 | 0.86 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL19479368 | 0.84 | LIPE (0.48) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL19480712 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL19484891 | 0.77 | BCHE (0.46) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL19485111 | 0.77 | BCHE (0.46) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL15960915 | 0.75 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL18963224 | 0.75 | MAOB (0.39) | ALDH1A1LMNAPSMB5TRPM8 | |
| SCHEMBL19479501 | 0.74 | BCHE (0.52) | ALDH1A1SMN1; SMN2TSHRHRH3SLC22A2 | |
| SCHEMBL9816878 | 0.74 | HTR2A (0.56) | ALDH1A1SMN1; SMN2TSHRHTR1AADRA2A | |
| SCHEMBL9816873 | 0.74 | HTR2A (0.56) | ALDH1A1SMN1; SMN2TSHRHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-09-29 | — | — | US | disclosed |
| US-20190112291-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | HCRTR1, HCRTR2, CNR1 | ALDH1A1 504/4885SMN1; SMN2 1231/4885TSHR 195/4885 |
| US-20190112291-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | HCRTR1, HCRTR2, CNR1 | ALDH1A1 589/4885SMN1; SMN2 1344/4885TSHR 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.