SCHEMBL2091073

SCHEMBL2091073

[CH2]COc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 14/20 0.60
L3MBTL1 Q9Y468 2/20 0.53
CALM1 P0DP23 1/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
HTT P42858 1/20 0.51
HRH3 Q9Y5N1 1/20 0.47
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
CASP3 P42574 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6468896 0.83 LTA4H (0.67) LTA4HL3MBTL1CYP1A2CYP2D6CYP2C9
SCHEMBL2093453 0.83 LMNA (0.67) LTA4HL3MBTL1CYP1A2CYP2C19LMNA
SCHEMBL933 0.81
SCHEMBL11856925 0.80 LMNA (0.69) LTA4HL3MBTL1CYP1A2CYP2C19LMNA
SCHEMBL10599543 0.80 LMNA (0.69) LTA4HL3MBTL1CYP1A2CYP2C19LMNA
SCHEMBL8672820 0.80 LTA4H (0.74) LTA4HL3MBTL1CALM1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL27692384 0.79 KCNA3 (0.55) LTA4HCYP2C9CYP2C19LMNA
SCHEMBL1912758 0.78 LTA4H (0.71) LTA4HL3MBTL1CALM1CYP1A2CYP2D6
SCHEMBL10062561 0.78 LTA4H (0.63) LTA4HL3MBTL1CALM1CYP1A2CYP2D6
SCHEMBL29127296 0.78 LTA4H (0.60) LTA4HL3MBTL1CALM1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4252716-A BLUE SHADES BAYER AKTIENGESELLSCHAFT (DE) 1981-02-24 US claimed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed
CN-112204073-B Polymeric material and intraocular lens 上海富吉医疗器械有限公司 2023-05-09 CN disclosed
CN-115073661-A Resin composition and display device using same 三星显示有限公司 2022-09-20 CN disclosed
US-20210292447-A1 POLYMER MATERIAL AND INTRAOCULAR LENS SHANGHAI FULO MEDICAL INSTRUMENT CO., LTD. (CN) 2021-09-23 US disclosed
EP-3805290-A1 POLYMER MATERIAL AND INTRAOCULAR LENS Shanghai Chartwell Medical Instrument Co., Ltd (CN) 2021-04-14 EP disclosed
CN-112204073-A Polymer material and intraocular lens 上海富吉医疗器械有限公司 2021-01-08 CN disclosed
WO-2019228224-A1 POLYMER MATERIAL AND INTRAOCULAR LENS 上海富吉医疗器械有限公司 (CN) 2019-12-05 WO disclosed
US-8163753-B2 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-04-24 US disclosed
EP-1678185-B1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMA CO LTD (JP) 2008-10-08 EP disclosed
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis OTSUKA PHAMACEUTICAL CO., LTD. (JP) 2008-05-22 US disclosed
US-5719306-A ANTIINFLAMMATORY AGENTS G.D. SEARLE & CO. (US) 1998-02-17 US disclosed
US-5717004-A COMPRISES ATLEAST TWO ACRYLOYL GROUP CONTAINING COMPOUNDS WHEREIN THE ACRYLOYL GROUP IS FLUOROACRYLOYL, METHACRYLOYL OR ACRYLOYL; HIGH MECHANICAL STRENGTH DAINIPPON INK & CHEMICALS, INC. (JP) 1998-02-10 US disclosed
EP-0435354-B1 Active energy ray-curable composition and applicable method DAINIPPON INK & CHEMICALS (JP) 1995-09-06 EP disclosed
EP-0289325-B1 METHOD OF INCREASING THE DYNAMICAL STRENGTH OF GLASS CONTAINER DAINIPPON INK AND CHEMICALS, INC. (JP) 1993-06-16 EP disclosed
EP-0435354-A2 Active energy ray-curable composition and applicable method DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-07-03 EP disclosed
US-4961976-A COATING WITH SILANE COUPLING AGENT AND ACRYLATED RESIN DAINIPPON INK & CHEMICALS, INC. (JP) 1990-10-09 US disclosed
US-4891241-A COUPLING AGENT, PHOTOPOLYMERIZABLE MONOMER DAINIPPON INK & CHEMICALS, INC. (JP) 1990-01-02 US disclosed
EP-0289325-A1 Method of increasing the dynamical strength of glass container DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-11-02 EP disclosed
EP-0004334-B1 CARBAMATES AND THEIR PESTICIDAL COMPOSITIONS, PREPARATIONS THEREOF AND USE THEREOF AS PESTICIDES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis NR2C2, NR0B2, NR4A2 LTA4H 3093/4885L3MBTL1 2575/4885CALM1 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.