Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009579 | 0.97 | LMNA (0.60) | LMNABLMALDH1A1PTPN1MEN1 | |
| SCHEMBL21925755 | 0.94 | LMNA (0.63) | LMNABLMALDH1A1PTPN1MEN1 | |
| SCHEMBL9945681 | 0.94 | LMNA (0.63) | LMNABLMALDH1A1PTPN1MEN1 | |
| SCHEMBL15290397 | 0.92 | LMNA (0.68) | LMNABLMALDH1A1PTPN1MEN1 | |
| SCHEMBL1023024 | 0.92 | LMNA (0.60) | LMNABLMALDH1A1PTPN1MEN1 | |
| SCHEMBL6746803 | 0.91 | LMNA (0.47) | LMNAALDH1A1GABBR2GABBR1OPRM1 | |
| SCHEMBL28391014 | 0.88 | LMNA (0.45) | LMNAALDH1A1GABBR2GABBR1OPRM1 | |
| SCHEMBL10343331 | 0.84 | LMNA (0.47) | LMNABLMALDH1A1GABBR2GABBR1 | |
| SCHEMBL23114851 | 0.82 | — | — | |
| SCHEMBL524521 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | VILNIUS UNIVERSITY (LT) | 2025-03-11 | — | — | US | disclosed |
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | VILNIUS UNIVERSITY (LT) | 2024-01-04 | — | — | US | disclosed |
| EP-4299062-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | Vilnius University (LT) | 2024-01-03 | — | — | EP | disclosed |
| US-11696953-B2 | Poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-11 | — | — | US | disclosed |
| US-20190110844-A1 | Apparatus And Methods Relating To Intravascular Positioning Of Distal End Of Catheter | BARD INC C R (US) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | APP, APBA1, IAPP | LMNA 1659/4885BLM 1135/4885ALDH1A1 3244/4885 |
| US-11696953-B2 | Poly(beta-amino esters) and uses thereof | BCAT1, BCAT2, SNRPE | LMNA 331/4885BLM 354/4885ALDH1A1 4132/4885 |
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | APP, APBA1, IAPP | LMNA 1659/4885BLM 1135/4885ALDH1A1 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.