Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925755 | 1.00 | LMNA (0.63) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL15290397 | 0.97 | LMNA (0.68) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL1023024 | 0.97 | LMNA (0.60) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL20912433 | 0.94 | LMNA (0.63) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL31009579 | 0.92 | LMNA (0.60) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL10343331 | 0.91 | LMNA (0.47) | LMNABLMALDH1A1GABBR2GABBR1 | |
| SCHEMBL6746803 | 0.84 | LMNA (0.47) | LMNAALDH1A1GABBR2GABBR1 | |
| SCHEMBL23355256 | 0.81 | — | — | |
| SCHEMBL4823250 | 0.81 | — | — | |
| SCHEMBL28391014 | 0.81 | LMNA (0.45) | LMNAALDH1A1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | VILNIUS UNIVERSITY (LT) | 2025-03-11 | — | — | US | disclosed |
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | VILNIUS UNIVERSITY (LT) | 2024-01-04 | — | — | US | disclosed |
| EP-4299062-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | Vilnius University (LT) | 2024-01-03 | — | — | EP | disclosed |
| EP-3505925-B1 | REAL-TIME AND QUANTITATIVE METHOD FOR MEASURING CELL TRACTION FORCE | UNIV HUNAN AGRICULTURAL (CN) | 2023-06-28 | — | — | EP | disclosed |
| US-20230002790-A1 | POLY(Beta-AMINO ESTER) NANOPARTICLES FOR THE NON-VIRAL DELIVERY OF PLASMID DNA FOR GENE EDITING AND RETINAL GENE THERAPY | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| US-20210388196-A1 | GENE DELIVERY CARRIER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-12-16 | — | — | US | disclosed |
| US-11041069-B2 | Gene delivery carrier | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200330396-A1 | NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE | THE JOHNS HOPKINS UNIVERSITY | 2020-10-22 | — | — | US | disclosed |
| US-20190194390-A1 | AMINO-POLYESTERS FOR DRUG DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-06-27 | — | — | US | disclosed |
| US-20190194444-A1 | GENE DELIVERY CARRIER | POLITECNICO DI MILANO (IT) | 2019-06-27 | — | — | US | disclosed |
| US-9777231-B2 | Hydrohalogenation of vinyl terminated polymers and their functionalized derivatives for fouling mitigation in hydrocarbon refining processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-10-03 | — | — | US | disclosed |
| US-9745528-B2 | Ring opening cross metathesis of vinyl terminated polymers and their functionalized derivatives for fouling mitigation in hydrocarbon refining processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-08-29 | — | — | US | disclosed |
| US-9714393-B2 | Ring opening cross metathesis of vinyl terminated polymers and their functionalized derivatives for fouling mitigation in hydrocarbon refining processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9663727-B2 | Functionalized polymers containing polyamine succinimide for antifouling in hydrocarbon refining processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-05-30 | — | — | US | disclosed |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-8562966-B2 | End-modified poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194444-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | LMNA 330/4885BLM 455/4885PTPN1 4812/4885 |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, POLL | LMNA 566/4885BLM 1330/4885PTPN1 2637/4885 |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | PARN, PARG, POLL | LMNA 566/4885BLM 1330/4885PTPN1 2637/4885 |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | LMNA 343/4885BLM 644/4885PTPN1 3992/4885 |
| US-11041069-B2 | Gene delivery carrier | PAICS, PBDC1, BCAT1 | LMNA 330/4885BLM 455/4885PTPN1 4812/4885 |
| US-20200330396-A1 | NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE | MYOC, MTREX, SLC26A4 | LMNA 402/4885BLM 1894/4885PTPN1 3497/4885 |
| US-20210388196-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | LMNA 330/4885BLM 455/4885PTPN1 4812/4885 |
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | APP, APBA1, IAPP | LMNA 1659/4885BLM 1135/4885PTPN1 3105/4885 |
| US-20190194390-A1 | AMINO-POLYESTERS FOR DRUG DELIVERY | DNPEP, NPEPPS, ANPEP | LMNA 2232/4885BLM 2240/4885PTPN1 4260/4885 |
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | APP, APBA1, IAPP | LMNA 1659/4885BLM 1135/4885PTPN1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.