SCHEMBL20916263

SCHEMBL20916263

CC(C)(C)c1ccccc1Nc1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
GAA P10253 6/20 0.50
ALDH1A1 P00352 6/20 0.50
KDM4E B2RXH2 3/20 0.50
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TDP1 Q9NUW8 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
APP P05067 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
SNCA P37840 1/20 0.47
BLM P54132 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29478037 1.00 MAPT (0.50) MAPTGAAALDH1A1KDM4EKMT2A
SCHEMBL29499693 0.87 ALDH1A1 (0.48) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL2818765 0.87 ALDH1A1 (0.48) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL24041234 0.85 KDM1A (0.50) MAPTGAAALDH1A1KDM4EKMT2A
SCHEMBL2677107 0.80 MAPT (0.71) MAPTGAAALDH1A1KDM4EKMT2A
SCHEMBL3159743 0.78 P2RY1 (0.53) MAPTSMN1; SMN2GRIN2DGRIN3BGRIN1
SCHEMBL28698942 0.77 MAPT (0.58) MAPTGAAALDH1A1KDM4EKMT2A
SCHEMBL25138272 0.76 KDM1A (0.45) MAPTGAAALDH1A1KDM4EKMT2A
SCHEMBL70170 0.75 TSHR (0.50) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL8962199 0.75 TDP1 (0.50) MAPTGAAALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124508-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-04-18 US disclosed
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 US disclosed
US-11725022-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-15 US disclosed
US-20220069239-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-03 US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed
US-20190119312-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124508-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 MAPT 884/4885GAA 1024/4885ALDH1A1 268/4885
US-11725022-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 MAPT 884/4885GAA 1024/4885ALDH1A1 268/4885
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 MAPT 884/4885GAA 1024/4885ALDH1A1 268/4885
US-20190119312-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 MAPT 884/4885GAA 1024/4885ALDH1A1 268/4885
US-20220069239-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE TPO, TTI1, TEAD1 MAPT 538/4885GAA 1601/4885ALDH1A1 56/4885
US-11802136-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 MAPT 884/4885GAA 1024/4885ALDH1A1 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.