Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994016 | 0.84 | MMP13 (0.41) | CTSKCTSSATMNR1H2NR1H3 | |
| SCHEMBL1096718 | 0.84 | MMP13 (0.41) | CTSKCTSSATMNR1H2NR1H3 | |
| SCHEMBL1096720 | 0.84 | MMP13 (0.41) | CTSKCTSSATMNR1H2NR1H3 | |
| SCHEMBL30361364 | 0.83 | NR1H2 (0.39) | CTSKCTSSATMNR1H2NR1H3 | |
| SCHEMBL16914053 | 0.82 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL27855088 | 0.81 | NR1H2 (0.44) | CTSKCTSSNR1H2NR1H3L3MBTL1 | |
| SCHEMBL8724217 | 0.81 | NR1H2 (0.39) | CTSKCTSSATMNR1H2NR1H3 | |
| SCHEMBL628088 | 0.81 | NR1H2 (0.44) | CTSKCTSSNR1H2NR1H3L3MBTL1 | |
| SCHEMBL7970722 | 0.78 | TRPM8 (0.42) | CTSKCTSSALOX5L3MBTL1CYP2D6 | |
| SCHEMBL2550637 | 0.78 | CCR5 (0.38) | CTSKCTSSATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077190-A1 | NEW PIRAZOLONE COMPOUNDS FOR THE DIAGNOSIS OF ALLERGIES TO BETA-LACTAM ANTIBIOTICS | SERVICIO ANDALUZ DE SALUD (ES) | 2019-04-25 | — | — | WO | disclosed |