Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28398877 | 0.90 | LTA4H (0.65) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL26850 | 0.87 | LTA4H (0.70) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL15162229 | 0.86 | NR1I2 (0.64) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL8298166 | 0.86 | LTA4H (0.61) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4241629 | 0.84 | NR5A1 (0.64) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL2092609 | 0.83 | ALDH1A1 (0.57) | LTA4HCYP3A4TP53CA1CA2 | |
| 1-Butyloxy-4-Propoxybenzene SCHEMBL23828869 | 0.82 | LTA4H (0.64) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL3727389 | 0.82 | NR5A1 (0.75) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| 1-Butyloxy-4-Pentoxybenzene SCHEMBL12827001 | 0.82 | NR5A1 (0.75) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| 1,4-Dipropoxybenzene SCHEMBL10846150 | 0.82 | LTA4H (0.64) | LTA4HNR5A1CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | LTA4H 3093/4885NR5A1 675/4885CYP3A4 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.