Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15B | O15296 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920201 | 0.91 | KDM4E (0.41) | ALOX15BL3MBTL1MAPTMAPK1ACHE | |
| SCHEMBL20917797 | 0.90 | MAPT (0.47) | ALOX15BL3MBTL1MAPTMAPK1MAOB | |
| SCHEMBL19019919 | 0.89 | HIF1A (0.47) | ALOX15BL3MBTL1MAPTMAPK1POLB | |
| SCHEMBL19061440 | 0.87 | MAPK1 (0.46) | MAPK1MAOBACHEBCHEBACE1 | |
| SCHEMBL19061872 | 0.81 | MAPK1 (0.41) | L3MBTL1MAPTMAPK1POLBGAA | |
| SCHEMBL22263137 | 0.81 | MAPK1 (0.50) | MAPK1GAAALDH1A1SIGMAR1LMNA | |
| SCHEMBL20917965 | 0.81 | MAPK1 (0.41) | L3MBTL1MAPTMAPK1GAAKDM4E | |
| SCHEMBL20932763 | 0.81 | MAPT (0.41) | ALOX15BL3MBTL1MAPTMAPK1MAOB | |
| SCHEMBL19061947 | 0.80 | P2RX7 (0.44) | MAPK1MAOBGAAALDH1A1LMNA | |
| SCHEMBL19019922 | 0.80 | MAPK1 (0.50) | MAPK1POLBGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | disclosed |