Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920185 | 0.91 | CYP1A2 (0.42) | MAPK1CYP1A2CYP2D6HIF1ASIGMAR1 | |
| SCHEMBL19061872 | 0.90 | MAPK1 (0.41) | MAPK1CYP1A2CYP2D6SIGMAR1OPRL1 | |
| SCHEMBL22263088 | 0.88 | CYP1A2 (0.42) | MAPK1CYP1A2CYP2D6HIF1ASIGMAR1 | |
| SCHEMBL19061440 | 0.86 | MAPK1 (0.46) | MAPK1SIGMAR1OPRL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22275605 | 0.84 | CYP1A2 (0.38) | MAPK1CYP1A2CYP2D6HIF1ADRD4 | |
| SCHEMBL19061947 | 0.84 | P2RX7 (0.44) | MAPK1KMT2AMEN1GFERSMN1; SMN2 | |
| SCHEMBL20920814 | 0.83 | SOS1 (0.39) | MAPK1CYP1A2CYP2D6HIF1ADRD4 | |
| SCHEMBL19019884 | 0.82 | MAPT (0.43) | MAPK1CYP1A2CYP2D6HIF1AOPRL1 | |
| SCHEMBL22263114 | 0.81 | CYP1A2 (0.43) | MAPK1CYP1A2CYP2D6HIF1ASIGMAR1 | |
| SCHEMBL20917786 | 0.81 | ALOX15B (0.46) | MAPK1HIF1ASIGMAR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | disclosed |