Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932763 | 0.91 | MAPT (0.41) | MAPTALDH1A1CYP2C19MAOBALOX15B | |
| SCHEMBL20917786 | 0.90 | ALOX15B (0.46) | MAPTALDH1A1MAOBALOX15BL3MBTL1 | |
| SCHEMBL22263101 | 0.85 | ALDH1A1 (0.49) | MAPTALDH1A1CYP2C19MAOBALOX15B | |
| SCHEMBL22262985 | 0.84 | GPR84 (0.38) | MAPTALDH1A1CYP2C19SCN9ASMN1; SMN2 | |
| SCHEMBL22275610 | 0.82 | PPARD (0.38) | MAPTALDH1A1CYP2C19SCN9ASMN1; SMN2 | |
| SCHEMBL22263183 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP2C19GAASMN1; SMN2RAB9A | |
| SCHEMBL19019919 | 0.81 | HIF1A (0.47) | MAPTALOX15BL3MBTL1CYP3A4MAPK1 | |
| SCHEMBL20917798 | 0.81 | SLC6A4 (0.36) | MAPTALDH1A1CYP2C19SCN9ASMN1; SMN2 | |
| SCHEMBL20920201 | 0.81 | KDM4E (0.41) | MAPTALDH1A1ALOX15BL3MBTL1GAA | |
| SCHEMBL20932777 | 0.78 | TAAR1 (0.45) | ALDH1A1CYP2C19GAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | CANBAS CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | IDO1, IDO2, TDO2 | MAPT 609/4885ALDH1A1 3331/4885CYP2C19 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.