Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Temefos SCHEMBL44105 | 0.85 | LMNA (0.53) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL23303378 | 0.85 | LMNA (0.53) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL6388031 | 0.84 | LMNA (0.51) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL8741692 | 0.84 | LMNA (0.51) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL10455340 | 0.82 | LMNA (0.47) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL15553439 | 0.79 | LMNA (0.51) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL10588833 | 0.78 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| Temefos SCHEMBL9809762 | 0.76 | LMNA (0.42) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| SCHEMBL14678662 | 0.76 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR | |
| SCHEMBL10937105 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255946-A1 | 2,4-DIOXO-1,4-DIHYDROTHIENOPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE | 日本曹達株式会社 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020241632-A1 | PYRIDINIUM SALT AND PEST CONTROL AGENT | 日本曹達株式会社 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020241626-A1 | PYRIDINIUM SALT AND PEST CONTROL AGENT | 日本曹達株式会社 | 2020-12-03 | — | — | WO | disclosed |
| EP-3697801-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | Bristol-Myers Squibb Company (US) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019079261-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-25 | — | — | WO | disclosed |