Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.38 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.38 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747998 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1TAAR1KMT2A | |
| SCHEMBL14120676 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1TAAR1KMT2A | |
| Hydrochloric Acid SCHEMBL14120623 | 0.98 | ALDH1A1 (0.52) | ALDH1A1CYP1A1CYP1B1TAAR1KMT2A | |
| Hydrochloric Acid SCHEMBL7788895 | 0.98 | ALDH1A1 (0.52) | ALDH1A1CYP1A1CYP1B1TAAR1KMT2A | |
| Hydrochloric Acid SCHEMBL3703308 | 0.98 | ALDH1A1 (0.52) | ALDH1A1CYP1A1CYP1B1TAAR1KMT2A | |
| SCHEMBL17040915 | 0.87 | TACR1 (0.46) | ALDH1A1TAAR1CYP3A4 | |
| SCHEMBL17041230 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TAAR1 | |
| SCHEMBL5281972 | 0.85 | ADRB2 (0.43) | ALDH1A1TAAR1SLC6A4 | |
| SCHEMBL4371381 | 0.85 | CYP3A4 (0.43) | ALDH1A1CYP1A1CYP1B1KMT2ACYP3A4 | |
| SCHEMBL3706661 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129041-A1 | MOLECULAR GLUE AND USES THEREOF | ASTROGEN, INC. (KR) | 2025-04-24 | — | — | US | disclosed |
| CN-110546150-B | Pyrazolyl-containing tricyclic derivatives, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-112020357-A | Salts of indazolyl-containing tricyclic derivatives and crystal forms thereof | 上海翰森生物医药科技有限公司 | 2020-12-01 | — | — | CN | disclosed |
| WO-2020200161-A1 | SALT OF INDAZOLYL-CONTAINING TRICYCLIC DERIVATIVE AND CRYSTAL FORM THEREOF | 上海翰森生物医药科技有限公司 | 2020-10-08 | — | — | WO | disclosed |
| EP-3699179-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2020-08-26 | — | — | EP | disclosed |
| US-20200247815-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2020-08-06 | — | — | US | disclosed |
| CN-110546150-A | Pyrazolyl-containing tricyclic derivatives, preparation method and application thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD | 2019-12-06 | — | — | CN | disclosed |
| WO-2019076336-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏豪森药业集团有限公司 | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129041-A1 | MOLECULAR GLUE AND USES THEREOF | ILK, FGB, UNC119 | ALDH1A1 1621/4885CYP1A1 4817/4885CYP1B1 4561/4885 |
| US-20200247815-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | MAPK1, MAPK11, MAPK14 | ALDH1A1 1717/4885CYP1A1 150/4885CYP1B1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.