Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23128488 | 0.71 | MAPT (0.40) | — | |
| SCHEMBL23432350 | 0.68 | EGFR (0.40) | — | |
| SCHEMBL20076486 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL7796081 | 0.66 | ALDH1A1 (0.32) | — | |
| SCHEMBL20387736 | 0.62 | ALDH1A1 (0.40) | — | |
| SCHEMBL3972895 | 0.60 | TRPA1 (0.41) | — | |
| SCHEMBL26759122 | 0.60 | NFE2L2 (0.34) | — | |
| SCHEMBL982304 | 0.59 | ALDH1A1 (0.41) | — | |
| SCHEMBL12763791 | 0.59 | ALDH1A1 (0.43) | — | |
| SCHEMBL982307 | 0.59 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327013-B1 | 5-SUBSTITUTED ISOINDOLINE COMPOUNDS | CELGENE CORP (US) | 2019-04-24 | — | — | EP | disclosed |