Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923811 | 0.96 | CHEK1 (0.40) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL20923766 | 0.95 | CHEK1 (0.37) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL20923579 | 0.92 | LMNA (0.36) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL20923082 | 0.92 | PDE3B (0.39) | FLT3LMNACYP2C19KDM4EPDE5A | |
| SCHEMBL20924100 | 0.91 | CYP11B1 (0.40) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL20923262 | 0.91 | CYP2C19 (0.37) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL19909026 | 0.91 | FLT3 (0.40) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL20923681 | 0.91 | CHEK1 (0.37) | CHEK1FLT3LMNACYP2C19KDM4E | |
| SCHEMBL20923089 | 0.88 | IMPDH2 (0.38) | LMNACYP2C19KDM4EPDE5AHPGD | |
| SCHEMBL20923859 | 0.88 | XDH (0.36) | CHEK1FLT3LMNACYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |