Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15026847 | 0.89 | SIGMAR1 (0.43) | ALDH1A1SIGMAR1DNM1SMN1; SMN2CHRM2 | |
| SCHEMBL15027494 | 0.85 | SIGMAR1 (0.40) | ALDH1A1SIGMAR1DNM1SMN1; SMN2CHRM2 | |
| SCHEMBL15027174 | 0.81 | DNM1 (0.46) | ALDH1A1DNM1SMN1; SMN2LMNA | |
| SCHEMBL12794350 | 0.81 | ALDH1A1 (0.68) | ALDH1A1USP2ALOX15TDP1SIGMAR1 | |
| SCHEMBL13743010 | 0.81 | ALDH1A1 (0.68) | ALDH1A1USP2ALOX15TDP1SIGMAR1 | |
| SCHEMBL12794352 | 0.81 | ALDH1A1 (0.68) | ALDH1A1USP2ALOX15TDP1SIGMAR1 | |
| SCHEMBL31226902 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SIGMAR1SMN1; SMN2LMNA | |
| SCHEMBL20924797 | 0.78 | SIGMAR1 (0.39) | ALDH1A1SIGMAR1DNM1SMN1; SMN2CHRM2 | |
| SCHEMBL15149624 | 0.78 | DNM1 (0.44) | ALDH1A1DNM1SMN1; SMN2LMNA | |
| SCHEMBL6521153 | 0.76 | ALDH1A1 (0.61) | ALDH1A1USP2ALOX15TDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788316-B1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2019-04-24 | — | — | EP | disclosed |