Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20928286 | 0.90 | FFAR1 (0.43) | FFAR1LTB4RLTB4R2L3MBTL1 | |
| SCHEMBL20928066 | 0.85 | FFAR1 (0.52) | FFAR1LTB4RLTB4R2 | |
| SCHEMBL20928062 | 0.85 | FFAR1 (0.52) | FFAR1LTB4RLTB4R2 | |
| SCHEMBL20928143 | 0.85 | MCL1 (0.38) | FFAR1LTB4RLTB4R2L3MBTL1LMNA | |
| SCHEMBL20928285 | 0.80 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL20928100 | 0.78 | L3MBTL1 (0.39) | L3MBTL1MCL1HCAR2F10F11 | |
| SCHEMBL20928061 | 0.78 | ALOX15B (0.50) | FFAR1LTB4RLTB4R2L3MBTL1MCL1 | |
| SCHEMBL20928099 | 0.77 | HCAR2 (0.39) | L3MBTL1MCL1HCAR2F10F11 | |
| SCHEMBL268963 | 0.76 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MCL1HCAR2 | |
| SCHEMBL30361685 | 0.76 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MCL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076343-A1 | PD-1/PD-L1 SMALL-MOLECULE INHIBITOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海长森药业有限公司 | 2019-04-25 | — | — | WO | disclosed |