SCHEMBL20928286 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	FFAR1	O14842	13/20	0.43

▸	LTB4R	Q15722	1/20	0.39

▸	LTB4R2	Q9NPC1	1/20	0.39

▸	CAMKK2	Q96RR4	1/20	0.38

▸	ESR1	P03372	1/20	0.37

▸	ESR2	Q92731	1/20	0.37

▸	KDM4C	Q9H3R0	2/20	0.37

▸	KDM6B	O15054	1/20	0.37

▸	L3MBTL1	Q9Y468	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20928142	0.90	FFAR1 (0.42)	FFAR1LTB4RLTB4R2L3MBTL1
SCHEMBL20928285	0.90	FFAR1 (0.42)	FFAR1
SCHEMBL20928062	0.83	FFAR1 (0.52)	FFAR1LTB4RLTB4R2
SCHEMBL20928066	0.83	FFAR1 (0.52)	FFAR1LTB4RLTB4R2
SCHEMBL20928143	0.81	MCL1 (0.38)	FFAR1LTB4RLTB4R2CAMKK2L3MBTL1
SCHEMBL20928100	0.75	L3MBTL1 (0.39)	CAMKK2L3MBTL1
SCHEMBL20928061	0.74	ALOX15B (0.50)	FFAR1LTB4RLTB4R2CAMKK2L3MBTL1
SCHEMBL268963	0.74	L3MBTL1 (0.59)	L3MBTL1
SCHEMBL30361685	0.74	L3MBTL1 (0.59)	L3MBTL1
SCHEMBL20928099	0.73	HCAR2 (0.39)	L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019076343-A1	PD-1/PD-L1 SMALL-MOLECULE INHIBITOR AND PREPARATION METHOD THEREFOR AND USE THEREOF	上海长森药业有限公司	2019-04-25	—	—	WO	disclosed