Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 9/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 3/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20927913 | 0.86 | PIK3C3 (0.51) | ADORA2AADORA1EGFRCSF1RKIT | |
| SCHEMBL20927912 | 0.81 | CDK5 (0.58) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL12330482 | 0.80 | CCNB2 (0.61) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL20928261 | 0.80 | EGFR (0.50) | EGFRRIPK1KIT | |
| SCHEMBL20928159 | 0.80 | MITF (0.47) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL1778024 | 0.80 | ADORA2A (0.56) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL31240593 | 0.80 | CDC7 (0.59) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL16041244 | 0.80 | CDC7 (0.59) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL3604759 | 0.80 | ADORA2A (0.56) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL20927949 | 0.80 | TBK1 (0.53) | CCNB2CDK1CCNB1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605460-A | Synthesis of heterocyclic compounds | 普莱希科公司（US） | 2023-01-13 | — | — | CN | disclosed |
| WO-2019079649-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | BLUEPRINT MEDICINES CORPORATION (US) | 2019-04-25 | — | — | WO | disclosed |