SCHEMBL20929080

SCHEMBL20929080

C/C=C1C(=C/C)\NC(C)(C)CC\1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24170699 0.84
SCHEMBL23183297 0.72 LMNA (0.31) ALDH1A1LMNAHPGD
SCHEMBL24187687 0.63
SCHEMBL17646863 0.63
SCHEMBL17646510 0.63
SCHEMBL9823449 0.63
SCHEMBL19297824 0.61 ALDH1A1 (0.38) ALDH1A1LMNAHPGDHTT
Hydrochloric Acid SCHEMBL8327324 0.61 ALDH1A1 (0.38) ALDH1A1LMNAHPGDHTT
SCHEMBL13213092 0.60 ALDH1A1 (0.33) ALDH1A1LMNAHPGDHTT
SCHEMBL30973127 0.58 ALDH1A1 (0.60) ALDH1A1LMNAHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11148995-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides STICHTING I-F PRODUCT COLLABORATION (NL) 2021-10-19 US disclosed
US-20200231533-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE COMPOUNDS AND RELATED AMINOINDANE AMIDES FMC IP TECHNOLOGY GMBH (CH) 2020-07-23 US disclosed
US-10640454-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides STICHTING I-F PRODUCT COLLABORATION (NL) 2020-05-05 US disclosed
US-20190119195-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES FMC IP TECHNOLOGY GMBH (CH) 2019-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10640454-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides AADAT, ALDH7A1, AAAS ALDH1A1 246/4885LMNA 3013/4885HPGD 46/4885
US-20190119195-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES ALDH7A1, AADAT, AASDHPPT ALDH1A1 229/4885LMNA 3054/4885HPGD 36/4885
US-11148995-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides AADAT, ALDH7A1, AAAS ALDH1A1 328/4885LMNA 2676/4885HPGD 47/4885
US-20200231533-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE COMPOUNDS AND RELATED AMINOINDANE AMIDES AADAT, ALDH7A1, AAAS ALDH1A1 328/4885LMNA 2676/4885HPGD 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.