Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536679 | 0.72 | MMP1 (0.37) | MMP1MMP2MMP9MMP12 | |
| SCHEMBL3933366 | 0.67 | CA12 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL98902 | 0.67 | MAOB (0.41) | — | |
| SCHEMBL95538 | 0.64 | IDO1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3251305 | 0.64 | IDO1 (0.52) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL7196008 | 0.63 | CA12 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL778583 | 0.63 | CA1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2093193 | 0.63 | CA12 (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL778189 | 0.63 | CA12 (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3691321 | 0.63 | MMP1 (0.44) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647581-A | Bicyclic pesticidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | claimed |
| EP-0084600-B1 | SUBSTITUTED BICYCLIC DERIVATIVES AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1986-06-25 | — | — | EP | claimed |
| EP-0084600-A1 | Substituted bicyclic derivatives and their use as insecticides | BAYER AG (DE) | 1983-08-03 | — | — | EP | claimed |
| EP-0004022-B1 | PENTAFLUOROBENZYLOXYCARBONYL DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES AND ACARICIDES | BAYER AG (DE) | 1981-09-16 | — | — | EP | claimed |
| JP-57098239-A | — | — | None | — | — | JP | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-4647581-A | Bicyclic pesticidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | disclosed |
| EP-0084600-B1 | SUBSTITUTED BICYCLIC DERIVATIVES AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1986-06-25 | — | — | EP | disclosed |
| US-4423066-A | MITICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| EP-0084600-A1 | Substituted bicyclic derivatives and their use as insecticides | BAYER AG (DE) | 1983-08-03 | — | — | EP | disclosed |
| JP-S5798239-A | PENTAFLUOROBENZYLOXYCARBONYL DERIVATIVE, AND INSECTICIDE CONTAINING IT AS ACTIVE INGREDIENT | NISSAN CHEM IND LTD | 1982-06-18 | — | — | JP | disclosed |
| EP-0004022-A1 | Pentafluorobenzyloxycarbonyl derivatives, method for their preparation and their use as insecticides and acaricides | BAYER AG (DE) | 1979-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | CA12 3179/4885CA1 4171/4885CA2 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.