Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063862 | 0.85 | ERN1 (0.47) | RAPGEF4ALDH1A1FFAR4LMNAKMT2A | |
| SCHEMBL28156106 | 0.84 | TPMT (0.50) | RAPGEF4ALDH1A1FFAR4LMNAKMT2A | |
| SCHEMBL8716465 | 0.81 | CYP3A4 (0.46) | RAPGEF4ALDH1A1LMNAKMT2A | |
| SCHEMBL7531476 | 0.81 | ALDH1A1 (0.39) | RAPGEF4ALDH1A1 | |
| SCHEMBL10501503 | 0.81 | ALDH1A1 (0.36) | RAPGEF4ALDH1A1 | |
| SCHEMBL16520251 | 0.81 | HMGB1 (0.38) | RAPGEF4ALDH1A1 | |
| SCHEMBL14858798 | 0.80 | ALDH1A1 (0.56) | RAPGEF4ALDH1A1LMNAKMT2A | |
| SCHEMBL12176175 | 0.79 | RAPGEF4 (0.57) | RAPGEF4ALDH1A1FFAR4 | |
| SCHEMBL20125107 | 0.79 | FFAR4 (0.42) | RAPGEF4ALDH1A1FFAR4LMNAKMT2A | |
| SCHEMBL10500612 | 0.78 | FFAR4 (0.47) | RAPGEF4ALDH1A1FFAR4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698697-A | A kind of triazole of claw type 1,4 connects cyclodextrin molecular and preparation method and application more | 昆明理工大学 | 2018-02-16 | — | — | CN | claimed |
| CN-104189951-B | A kind of injection quickly forms liquid formulation of micro-molecular hydrogel in situ and its preparation method and application | 赣南师范学院 | 2017-06-30 | — | — | CN | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| CN-109456216-A | A kind of no catalyst is reacted without aromatic amine under the conditions of promotor with the amine that turns of amide derivatives | 湘潭大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-104189951-B | A kind of injection quickly forms liquid formulation of micro-molecular hydrogel in situ and its preparation method and application | 赣南师范学院 | 2017-06-30 | — | — | CN | disclosed |
| CN-104189951-B | A kind of injection quickly forms liquid formulation of micro-molecular hydrogel in situ and its preparation method and application | 赣南师范学院 | 2017-06-30 | — | — | CN | disclosed |
| EP-2632929-A1 | N-HETEROCYCLIC CARBENE COMPLEXES, THEIR PREPARATION AND USE | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| CN-103180332-A | N-heterocyclic carbene complexes, preparation and application thereof | BASF SE | 2013-06-26 | — | — | CN | disclosed |
| US-8455252-B2 | Materials and methods for sensitizing multidrug resistant cells | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| WO-1996003385-A1 | 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |
| EP-0679157-A1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994015932-A1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1994-07-21 | — | — | WO | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |
| US-3979385-A | HEAVY METAL COMPLEXING AGENTS | HENKEL & CIE G.M.B.H. (DT) | 1976-09-07 | — | — | US | disclosed |