SCHEMBL20935877

SCHEMBL20935877

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1cccc2ccccc12)c1ccccc1C31c2ccsc2-c2sccc21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.32
ELANE P08246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20935769 0.87
SCHEMBL20935766 0.85 ALOX5 (0.30)
SCHEMBL20935721 0.85 PGR (0.33) MEN1KMT2A
SCHEMBL20935765 0.85 PRKDC (0.31) MEN1KMT2A
SCHEMBL20915067 0.84 PGR (0.31)
SCHEMBL28623453 0.83 POLB (0.43) POLBMEN1MAPTKMT2AKDM4E
SCHEMBL20935767 0.83
SCHEMBL20915065 0.83 PGR (0.30)
SCHEMBL20935876 0.82 PGR (0.32)
SCHEMBL24689208 0.79 POLB (0.43) POLBMEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190123284-A1 POLYHETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190123284-A1 POLYHETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DDT, ALKBH1, PPOX POLB 1409/4885MEN1 4338/4885MAPT 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.