Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917763 | 0.82 | KDM4E (0.50) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8446966 | 0.70 | ALDH1A1 (0.52) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL15591268 | 0.69 | KDM4E (0.50) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14035628 | 0.68 | GRIK2 (0.59) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL17266949 | 0.67 | ALDH1A1 (0.49) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28010239 | 0.66 | TSHR (0.61) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL20853323 | 0.64 | CA12 (0.39) | KDM4EHPGDL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2807198 | 0.62 | CYP3A4 (0.48) | KDM4EHPGDL3MBTL1ALDH1A1MAPT | |
| Biphenyl SCHEMBL8734478 | 0.62 | ALDH1A1 (0.50) | HPGDL3MBTL1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9664824 | 0.62 | CYP19A1 (0.50) | KDM4EHPGDL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |