SCHEMBL20944007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27758051	0.82	KDM4E (0.42)	HSD17B10TSHRKDM4EALDH1A1HPGD
	SCHEMBL7986113	0.81	PDE5A (0.48)	FNTAFNTBHSD17B10TSHRKDM4E
	SCHEMBL20943940	0.78	ALDH1A1 (0.51)	HSD17B10TSHRKDM4EALDH1A1DPP4
	SCHEMBL6883767	0.74	TSHR (0.55)	HSD17B10TSHRKDM4EATMGLA
	SCHEMBL509507	0.74	ACHE (0.52)	KDM4EALDH1A1HPGDCYP1A2CYP3A4
	SCHEMBL12326381	0.74	KDM4E (0.51)	HSD17B10TSHRKDM4EATMGLA
	SCHEMBL3681739	0.72	KDM4E (0.50)	HSD17B10TSHRKDM4EATMGLA
	SCHEMBL2900687	0.72	KMT2A (0.65)	TSHRKDM4EALDH1A1DPP4KMT2A
	SCHEMBL7390366	0.72	MAPT (0.45)	FNTAFNTBKDM4EGLAALDH1A1
	SCHEMBL7671086	0.72	MAOB (0.53)	FNTAFNTBHSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.