Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084274 | 0.93 | SIRT2 (0.52) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL23907113 | 0.87 | SIRT2 (0.46) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11510186 | 0.78 | PTGS2 (0.54) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL1879712 | 0.76 | GAA (0.53) | ALDH1A1GAACYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13832484 | 0.75 | NFE2L2 (0.53) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3366755 | 0.75 | SIRT2 (0.81) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL12851394 | 0.75 | PTGS2 (0.55) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7883088 | 0.75 | PTGS2 (0.51) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7883092 | 0.75 | PTGS2 (0.51) | PTGS2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28964182 | 0.75 | MAPT (0.54) | PTGS2SIRT2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20220199908-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | US | disclosed |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| US-20210147375-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-10273404-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2E1, GPX1, ERCC1 | PTGS2 2425/4885SIRT2 2977/4885KMT2A 2053/4885 |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, ETV6, ESR1 | PTGS2 2514/4885SIRT2 2795/4885KMT2A 1666/4885 |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | PTGS2 2684/4885SIRT2 3433/4885KMT2A 1528/4885 |
| US-20210147375-A1 | MATERIALS FOR ELECTRONIC DEVICES | PNMT, EFNA1, TES | PTGS2 3708/4885SIRT2 2753/4885KMT2A 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.