Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567235 | 0.99 | LMNA (0.37) | LMNAKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL28578629 | 0.99 | LMNA (0.37) | LMNAKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20981867 | 0.88 | TDP1 (0.35) | TDP1CYP3A4 | |
| SCHEMBL20955365 | 0.87 | TDP1 (0.34) | TDP1CYP3A4 | |
| Lithium Ion SCHEMBL20955373 | 0.87 | KDM4E (0.33) | LMNAKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20955402 | 0.87 | TDP1 (0.34) | TDP1CYP3A4 | |
| SCHEMBL20955405 | 0.87 | KDM4E (0.33) | LMNAKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20955536 | 0.85 | NQO2 (0.36) | LMNAKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20955534 | 0.84 | TSHR (0.35) | TDP1 | |
| SCHEMBL20955438 | 0.84 | TDP1 (0.32) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3479696-B1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | MOGHU RES CENTER LTD (KR) | 2021-06-09 | — | — | EP | claimed |
| CN-109561682-B | Pyridines comprising an isoxazoline ring and their use as herbicides | 牧牛研究所株式会社 | 2021-05-11 | — | — | CN | claimed |
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | MOGHU RESEARCH CENTER LTD. (KR) | 2019-05-30 | — | — | US | claimed |
| EP-3479696-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | Moghu Research Center Ltd. (KR) | 2019-05-08 | — | — | EP | claimed |
| EP-3479696-B1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | MOGHU RES CENTER LTD (KR) | 2021-06-09 | — | — | EP | disclosed |
| CN-109561682-B | Pyridines comprising an isoxazoline ring and their use as herbicides | 牧牛研究所株式会社 | 2021-05-11 | — | — | CN | disclosed |
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | MOGHU RESEARCH CENTER LTD. (KR) | 2019-05-30 | — | — | US | disclosed |
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | MOGHU RESEARCH CENTER LTD. (KR) | 2019-05-30 | — | — | US | disclosed |
| EP-3479696-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | Moghu Research Center Ltd. (KR) | 2019-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | CYP4X1, CYP3A7, IDH2 | LMNA 4732/4885KDM4E 861/4885ALDH1A1 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.