Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL20955373 | 0.97 | KDM4E (0.33) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL20955347 | 0.87 | LMNA (0.38) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL28578629 | 0.86 | LMNA (0.37) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL28567235 | 0.86 | LMNA (0.37) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL20955536 | 0.85 | NQO2 (0.36) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| Lithium Ion SCHEMBL20996700 | 0.85 | FAAH (0.31) | — | |
| SCHEMBL20955483 | 0.80 | ALDH1A1 (0.34) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL20955266 | 0.80 | GLP1R (0.37) | KDM4EALDH1A1TP53LMNA | |
| SCHEMBL20996703 | 0.78 | FAAH (0.34) | KDM4EALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL20955272 | 0.78 | GPR35 (0.32) | KDM4EALDH1A1TP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3479696-B1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | MOGHU RES CENTER LTD (KR) | 2021-06-09 | — | — | EP | claimed |
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | MOGHU RESEARCH CENTER LTD. (KR) | 2019-05-30 | — | — | US | claimed |
| EP-3479696-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | Moghu Research Center Ltd. (KR) | 2019-05-08 | — | — | EP | claimed |
| EP-3479696-B1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | MOGHU RES CENTER LTD (KR) | 2021-06-09 | — | — | EP | disclosed |
| CN-109561682-B | Pyridines comprising an isoxazoline ring and their use as herbicides | 牧牛研究所株式会社 | 2021-05-11 | — | — | CN | disclosed |
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | MOGHU RESEARCH CENTER LTD. (KR) | 2019-05-30 | — | — | US | disclosed |
| EP-3479696-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE | Moghu Research Center Ltd. (KR) | 2019-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190159450-A1 | PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE | CYP4X1, CYP3A7, IDH2 | KDM4E 861/4885ALDH1A1 86/4885TP53 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.