SCHEMBL20955844

SCHEMBL20955844

N#Cc1ccc(-c2ccccc2)c(-c2ccccc2)c1P

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
ALDH1A1 P00352 7/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GALR3 O60755 1/20 0.38
GAA P10253 1/20 0.38
ESR2 Q92731 1/20 0.38
LRRK2 Q5S007 1/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
THRB P10828 1/20 0.36
MDM2 Q00987 1/20 0.35
AR P10275 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29913927 1.00 MAOA (0.40) MAOAMAOBALDH1A1HPGDKDM4E
SCHEMBL10935465 0.80 LMNA (0.42) ALDH1A1HPGDESR2LMNAHTT
SCHEMBL11163889 0.79 ADORA2A (0.45) MAOAMAOBALDH1A1HPGDKDM4E
SCHEMBL1285671 0.78 MAOA (0.50) MAOAMAOBALDH1A1HPGDKDM4E
SCHEMBL565466 0.75 ESR2 (0.50) ALDH1A1HPGDKDM4ECYP1A2CYP2C9
SCHEMBL31663575 0.74 ADORA1 (0.46) ALDH1A1HPGDKDM4ECYP1A2CYP2C9
SCHEMBL31663612 0.74 ADORA1 (0.46) ALDH1A1HPGDKDM4ECYP1A2CYP2C9
SCHEMBL2350899 0.72 IMPDH2 (0.50) MAOAMAOBALDH1A1HPGDKDM4E
Water SCHEMBL28835132 0.72 LMNA (0.48) ALDH1A1HPGDESR2LMNAHTT
SCHEMBL18411313 0.72 ESR2 (0.47) MAOAMAOBALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480204-B1 ORGANIC MAGNESIUM PHOSPHIDE AND METHOD FOR PRODUCING SAME, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ORGANIC PHOSPHORUS-CONTAINING COMPOUND USING SAID PHOSPHIDE HOKKO CHEM IND CO (JP) 2022-09-07 EP disclosed
US-20190248815-A1 ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2019-08-15 US disclosed
EP-3480204-A1 ORGANIC MAGNESIUM PHOSPHIDE AND METHOD FOR PRODUCING SAME, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ORGANIC PHOSPHORUS-CONTAINING COMPOUND USING SAID PHOSPHIDE Hokko Chemical Industry Co., Ltd. (JP) 2019-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248815-A1 ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE IPMK, PPIP5K2, PIP4K2C MAOA 2894/4885MAOB 1742/4885ALDH1A1 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.