Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349820 | 0.78 | PARP1 (0.60) | TPMTRAB9AHCAR1TSHRPARP1 | |
| SCHEMBL4465360 | 0.77 | TPMT (0.65) | TPMTRAB9AHCAR1TSHRPARP1 | |
| Hydrochloric Acid SCHEMBL4371939 | 0.76 | PARP1 (0.58) | TPMTRAB9AHCAR1TSHRPARP1 | |
| SCHEMBL11048208 | 0.76 | HPGD (0.43) | TPMTRAB9ATSHR | |
| SCHEMBL1196056 | 0.75 | PARP1 (0.69) | RAB9APARP1FLT1FLT4KDR | |
| SCHEMBL23699 | 0.74 | TPMT (1.00) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL2170895 | 0.74 | TPMT (0.62) | TPMTRAB9AHCAR1TSHRPARP1 | |
| SCHEMBL19998298 | 0.74 | TPMT (0.62) | TPMTRAB9AHCAR1TSHRPARP1 | |
| SCHEMBL93282 | 0.74 | TPMT (0.62) | TPMTRAB9AHCAR1TSHRPARP1 | |
| SCHEMBL28214359 | 0.74 | TPMT (1.00) | TPMTHCAR1TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031573-B2 | USE OF A BENZOYLPYRAZOLE COMPOUND AS HERBICIDE | NIPPON SODA CO (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1031573-B1 | NOVEL BENZOYLPYRAZOLE COMPOUNDS, INTERMEDIATES, AND HERBICIDES | NIPPON SODA CO (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| CN-1141306-C | Novel benzoylpyrazole compound, production intermediate and herbicide | �ձ�������ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1278259-A | Novel benzoylpyrazole compound, production intermediate and herbicide | NIPPON SODA CO (JP) | 2000-12-27 | — | — | CN | disclosed |
| US-6147031-A | Benzoylpyrazole compounds, intermediate preparing therefor and herbicides | NIPPON SODA CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-1031573-A1 | NOVEL BENZOYLPYRAZOLE COMPOUNDS, INTERMEDIATES, AND HERBICIDES | NIPPON SODA CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | TPMT 2767/4885RAB9A 3153/4885HCAR1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.