SCHEMBL2095803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2095800	1.00	ALDH1A1 (0.47)	ALDH1A1HDAC1HDAC8HDAC6GSR
	SCHEMBL2092516	0.85	PTGS2 (0.39)	ALDH1A1HDAC1GRIK1GRIK2MAPT
	SCHEMBL2092514	0.85	PTGS2 (0.39)	ALDH1A1HDAC1GRIK1GRIK2MAPT
	SCHEMBL5535064	0.78	TDP1 (0.37)	ALDH1A1MAPTMEN1KMT2AMAOB
	SCHEMBL2096137	0.78	TDP1 (0.50)	ALDH1A1MAPTNPC1RAB9AMEN1
	SCHEMBL5535065	0.78	TDP1 (0.37)	ALDH1A1MAPTMEN1KMT2AMAOB
	SCHEMBL2096134	0.78	TDP1 (0.50)	ALDH1A1MAPTNPC1RAB9AMEN1
	SCHEMBL2095735	0.78	HDAC1 (0.47)	ALDH1A1HDAC1HDAC8HDAC6GSR
	SCHEMBL2095732	0.78	HDAC1 (0.47)	ALDH1A1HDAC1HDAC8HDAC6GSR
	SCHEMBL2091749	0.77	HSD11B1 (0.48)	ALDH1A1MAPTNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.