SCHEMBL20958253

SCHEMBL20958253

C[Si](C)(C)c1cc(C(c2cc([Si](C)(C)C)c(O)c([Si](C)(C)C)c2)(C(F)(F)F)C(F)(F)F)cc([Si](C)(C)C)c1O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247818 0.73 ESR1 (0.48) ESR1ESR2
SCHEMBL3680776 0.69 ESR1 (0.46) ESR1ESR2
SCHEMBL20958241 0.68 CA2 (0.54) ESR1ESR2
SCHEMBL4575336 0.67
SCHEMBL6844032 0.67 HSD17B10 (0.46) ESR1ESR2NR1H2NR1H3
SCHEMBL7766964 0.67 TSHR (0.54) ESR1ESR2
SCHEMBL20958248 0.67 GABRA1 (0.46) ESR1ESR2
SCHEMBL20987878 0.67 CA1 (0.52) ESR1ESR2
SCHEMBL9764127 0.67 PKM (0.44) ESR1ESR2
SCHEMBL19765496 0.65 ESR1 (0.43) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11738327-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-08-29 US disclosed
US-11654415-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-23 US disclosed
US-11648529-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-16 US disclosed
US-20220258126-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-18 US disclosed
US-20220258125-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-18 US disclosed
US-20220241750-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-04 US disclosed
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-05-10 US disclosed
EP-3706899-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS The Government Of The United States Of America As The Secretary of The Navy (US) 2020-09-16 EP disclosed
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11648529-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-20220258126-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-20220258125-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-20220241750-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-11654415-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-11738327-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885NR1H2 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.