Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20967821 | 0.89 | ESR1 (0.54) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL15869211 | 0.86 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL15869212 | 0.84 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL12204977 | 0.79 | ESR1 (0.65) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL21953155 | 0.78 | ESR1 (0.54) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL19872008 | 0.73 | ADORA3 (0.60) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL12101644 | 0.73 | ADORA3 (0.56) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL19200571 | 0.72 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL21785623 | 0.71 | ADORA3 (0.54) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 | |
| SCHEMBL19431650 | 0.71 | ADORA3 (0.65) | SLC6A4SLC6A3SLC6A2ADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3477394-B1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2020-09-09 | — | — | EP | disclosed |
| WO-2020084900-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | 京セラドキュメントソリューションズ株式会社 | 2020-04-30 | — | — | WO | disclosed |
| EP-3477394-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA Document Solutions Inc. (JP) | 2019-05-01 | — | — | EP | disclosed |