Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21953155 | 0.89 | ESR1 (0.54) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL20959904 | 0.89 | SLC6A4 (0.49) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL12204977 | 0.83 | ESR1 (0.65) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL20671282 | 0.78 | ADORA3 (0.61) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL12205413 | 0.78 | ADORA3 (0.61) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL22244363 | 0.78 | ADORA3 (0.61) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL21085480 | 0.77 | ESR1 (0.77) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL8760127 | 0.75 | ESR2 (0.71) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL15869211 | 0.74 | SLC6A4 (0.61) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL21216068 | 0.74 | ESR1 (0.45) | ESR1ESR2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10359714-B2 | Electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-07-23 | — | — | US | disclosed |
| US-20190129321-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-05-02 | — | — | US | disclosed |