Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20967821 | 0.89 | ESR1 (0.54) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL12204977 | 0.83 | ESR1 (0.65) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL20959904 | 0.78 | SLC6A4 (0.49) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL12205413 | 0.78 | ADORA3 (0.61) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL20671282 | 0.78 | ADORA3 (0.61) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL22244363 | 0.78 | ADORA3 (0.61) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL20320025 | 0.75 | ESR2 (0.53) | ESR1ESR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8760127 | 0.75 | ESR2 (0.71) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL21085480 | 0.74 | ESR1 (0.77) | ESR1ESR2ADORA3SLC6A4SLC6A3 | |
| SCHEMBL15869211 | 0.74 | SLC6A4 (0.61) | ESR1ESR2ADORA3SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10635009-B2 | Electrophotographic photosensitive member, process cartridge, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-28 | — | — | US | disclosed |