SCHEMBL2096154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8116436	0.82	SMN1; SMN2 (0.50)	NPC1RAB9AMEN1KMT2ASMN1; SMN2
	SCHEMBL1536381	0.81	CES2 (0.59)	CES2CES1NPC1RAB9APARP1
	SCHEMBL1536382	0.81	CES2 (0.59)	CES2CES1NPC1RAB9APARP1
	SCHEMBL2093430	0.81	TAS1R3 (0.46)	NPC1RAB9AMAOB
	SCHEMBL14376098	0.80	CES2 (0.62)	CES2CES1NPC1RAB9APARP1
	SCHEMBL2089059	0.79	ALDH1A1 (0.50)	NPC1RAB9AMEN1KMT2ASMN1; SMN2
	SCHEMBL28366248	0.78	NPC1 (0.61)	CES2CES1NPC1RAB9APARP1
	SCHEMBL2092794	0.78	CES2 (0.60)	CES2CES1NPC1RAB9APARP1
	SCHEMBL9519194	0.78	NPC1 (0.61)	CES2CES1NPC1RAB9APARP1
	SCHEMBL2599124	0.77	PRSS1 (0.47)	CES2CES1NPC1RAB9APARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.