Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 2/20 | 0.48 |
| ▸ | KISS1R | Q969F8 | 12/20 | 0.48 |
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964470 | 0.88 | MMP2 (0.53) | KISS1R | |
| SCHEMBL20964469 | 0.88 | CTSL (0.49) | QRFPRKISS1RCTSL | |
| SCHEMBL10741046 | 0.82 | FCER2 (0.50) | KISS1R | |
| SCHEMBL10741034 | 0.82 | FCER2 (0.50) | KISS1R | |
| SCHEMBL20964486 | 0.81 | UTS2R (0.52) | KISS1RCTSL | |
| SCHEMBL20964440 | 0.81 | KISS1R (0.48) | QRFPRKISS1RCTSL | |
| SCHEMBL20964474 | 0.80 | MMP2 (0.50) | CTSL | |
| SCHEMBL29618668 | 0.80 | NPY1R (0.64) | QRFPRKISS1R | |
| SCHEMBL20964466 | 0.80 | QRFPR (0.44) | QRFPRKISS1R | |
| SCHEMBL20964460 | 0.79 | MMP2 (0.53) | KISS1RCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220526-B2 | Neuropeptide S receptor (NPSR) agonists | RESEARCH TRIANGLE INSTITUTE (US) | 2022-01-11 | — | — | US | disclosed |
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | RESEARCH TRIANGLE INSTITUTE | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | NPSR1, GRPR, NPBWR1 | QRFPR 24/4885KISS1R 146/4885EED 4024/4885 |
| US-11220526-B2 | Neuropeptide S receptor (NPSR) agonists | NPSR1, GRPR, NPBWR1 | QRFPR 24/4885KISS1R 146/4885EED 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.