Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964424 | 0.88 | GHSR (0.55) | GHSRCTSL | |
| SCHEMBL20964474 | 0.86 | MMP2 (0.50) | GHSRSSTR3CTSL | |
| SCHEMBL20964425 | 0.85 | CALCRL (0.53) | SSTR3KISS1RPTPN1 | |
| SCHEMBL20964476 | 0.85 | QRFPR (0.49) | GHSRGNPATKISS1RCTSL | |
| SCHEMBL20964453 | 0.85 | PTPN1 (0.57) | PTPN2PTPN1CTSL | |
| SCHEMBL20964423 | 0.85 | PRSS1 (0.61) | GHSRKISS1RCTSL | |
| SCHEMBL20964469 | 0.84 | CTSL (0.49) | GHSRKISS1RCTSL | |
| SCHEMBL20964460 | 0.83 | MMP2 (0.53) | GHSRKISS1RCTSL | |
| SCHEMBL25062471 | 0.83 | TLR2 (0.57) | GHSRSSTR3GNPATCPB2KLKB1 | |
| SCHEMBL20964475 | 0.83 | CALCRL (0.52) | KISS1RCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220526-B2 | Neuropeptide S receptor (NPSR) agonists | RESEARCH TRIANGLE INSTITUTE (US) | 2022-01-11 | — | — | US | disclosed |
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | RESEARCH TRIANGLE INSTITUTE | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | NPSR1, GRPR, NPBWR1 | GHSR 14/4885SSTR3 56/4885GNPAT 2144/4885 |
| US-11220526-B2 | Neuropeptide S receptor (NPSR) agonists | NPSR1, GRPR, NPBWR1 | GHSR 14/4885SSTR3 56/4885GNPAT 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.