Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964547 | 0.85 | GAA (0.56) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL20964662 | 0.84 | SMN1; SMN2 (0.60) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27936738 | 0.79 | KMT2A (0.66) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL20964672 | 0.78 | MAPT (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1491206 | 0.77 | KMT2A (0.64) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27918158 | 0.77 | KMT2A (0.64) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4019882 | 0.76 | GAA (0.70) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11120307 | 0.76 | GAA (0.70) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3801245 | 0.76 | GAA (0.65) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19049601 | 0.76 | KMT2A (0.62) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | KMT2A 4728/4885MEN1 179/4885GAA 57/4885 |
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | SERPINC1, F12, RPL35 | KMT2A 3241/4885MEN1 2387/4885GAA 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.