Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964693 | 0.87 | KDM4E (0.49) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL9313923 | 0.85 | MEN1 (0.68) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL30022414 | 0.84 | RAB9A (0.54) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL7264600 | 0.82 | ALDH1A1 (0.73) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL10176583 | 0.82 | MEN1 (0.59) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL13018987 | 0.82 | KDM4E (0.52) | MEN1KMT2ARAB9AKDM4ETSHR | |
| SCHEMBL31570084 | 0.81 | MEN1 (0.57) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL9292088 | 0.81 | MEN1 (0.57) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL23130363 | 0.80 | RAB9A (0.53) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL22722429 | 0.79 | POLB (0.59) | MEN1KMT2ARAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | MEN1 179/4885KMT2A 4728/4885RAB9A 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.