Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936752 | 0.80 | HTT (0.58) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL1541692 | 0.78 | TAAR1 (0.57) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL3511543 | 0.78 | HTT (0.56) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL6932504 | 0.78 | L3MBTL1 (0.57) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL18065741 | 0.78 | HTT (0.51) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL13621571 | 0.78 | TAAR1 (0.57) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL7039441 | 0.78 | HTT (0.51) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL13621464 | 0.78 | TAAR1 (0.57) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL3204506 | 0.77 | CYP1A2 (0.72) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 | |
| SCHEMBL17465576 | 0.77 | L3MBTL1 (0.65) | HTTL3MBTL1SMN1; SMN2ALDH1A1NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | claimed |
| US-8163769-B2 | 1,8-naphthyridine derivatives | ABBOTT LABORATORIES (US) | 2012-04-24 | — | — | US | disclosed |
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | PGLS, UGT1A1, CASP1 | HTT 4675/4885L3MBTL1 1277/4885SMN1; SMN2 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.