Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14692527 | 0.89 | GPR119 (0.46) | GPR119DDB1CRBNHTTATM | |
| SCHEMBL23911654 | 0.87 | KDM4E (0.47) | GPR119DDB1CRBNIRAK4CTSD | |
| SCHEMBL23911653 | 0.84 | KDM5C (0.49) | GPR119DDB1CRBNKDM4E | |
| SCHEMBL18376153 | 0.84 | GPR119 (0.47) | GPR119DDB1CRBNHTTATM | |
| SCHEMBL16716871 | 0.82 | GPR119 (0.46) | GPR119DDB1CRBNCTSDCTSE | |
| SCHEMBL18367623 | 0.82 | GPR119 (0.46) | GPR119DDB1CRBNHTTATM | |
| SCHEMBL22875377 | 0.82 | HTT (0.45) | GPR119DDB1CRBNCTSDCTSE | |
| SCHEMBL22730550 | 0.81 | DDB1 (0.48) | GPR119DDB1CRBNHTTATM | |
| SCHEMBL21410874 | 0.81 | HTT (0.46) | GPR119DDB1CRBNHTTATM | |
| SCHEMBL6071289 | 0.81 | DDB1 (0.45) | GPR119DDB1CRBNCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317113-A1 | 1,2,3-TRIAZOLE DERIVATIVES AND USES THEREOF | Alxerion Biotech LLC | 2021-10-14 | — | — | US | disclosed |
| US-10703748-B2 | Diazanaphthalen-3-yl carboxamides and preparation and use thereof | SAMUMED, LLC (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190127370-A1 | DIAZANAPHTHALEN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | VICKERS-SPLICE CO-INVESTMENT LLC (KY) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317113-A1 | 1,2,3-TRIAZOLE DERIVATIVES AND USES THEREOF | CYP3A43, CYP51A1, CYP11B2 | GPR119 4605/4885DDB1 3333/4885CRBN 2486/4885 |
| US-20190127370-A1 | DIAZANAPHTHALEN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | DYRK1A, DKK1, WNT1 | GPR119 830/4885DDB1 495/4885CRBN 548/4885 |
| US-10703748-B2 | Diazanaphthalen-3-yl carboxamides and preparation and use thereof | DYRK1A, DKK1, WNT1 | GPR119 830/4885DDB1 495/4885CRBN 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.