SCHEMBL20967601

SCHEMBL20967601

C/C=C\c1c(/N=C\C)oc2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.36
MAPT P10636 5/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 5/20 0.34
HPGD P15428 4/20 0.34
CASP3 P42574 2/20 0.34
SENP7 Q9BQF6 2/20 0.34
MAOB P27338 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
PGAM1 P18669 1/20 0.33
MAOA P21397 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19731970 0.83 MAOB (0.37) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL19538054 0.83 KDM4E (0.35) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL25986408 0.82 MAOB (0.36) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL20967607 0.79 L3MBTL1 (0.40) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL18685767 0.77 KDM4E (0.47) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL12646572 0.75 L3MBTL1 (0.37) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL22435817 0.71 EYA3 (0.43) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL17192976 0.71 L3MBTL1 (0.37) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL22454544 0.70 ESR2 (0.34) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL21117505 0.70 MAOA (0.50) KDM4EMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2019-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 KDM4E 1361/4885MAPT 4528/4885MEN1 1139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.