Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 1/20 | 0.70 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969601 | 0.92 | KARS1 (0.59) | KARS1LPAR1LPAR5TAS2R14PPARD | |
| SCHEMBL20969751 | 0.92 | KARS1 (0.59) | KARS1LPAR1LPAR5TAS2R14PPARD | |
| SCHEMBL20969641 | 0.91 | KARS1 (0.59) | KARS1LPAR1LPAR5TAS2R14PPARD | |
| SCHEMBL20969618 | 0.91 | KARS1 (0.60) | KARS1LPAR1LPAR5PPARDALOX5 | |
| SCHEMBL31130495 | 0.91 | KARS1 (0.57) | KARS1PPARDPPARGPPARA | |
| SCHEMBL20969554 | 0.90 | KARS1 (0.55) | KARS1LPAR1LPAR5PPARDALOX5 | |
| SCHEMBL20969715 | 0.90 | KARS1 (0.57) | KARS1LPAR1LPAR5TAS2R14PPARD | |
| SCHEMBL20969608 | 0.90 | KARS1 (0.57) | KARS1LPAR1LPAR5PPARDALOX5 | |
| SCHEMBL20969689 | 0.90 | KARS1 (0.71) | KARS1LPAR1LPAR5TAS2R14PPARD | |
| SCHEMBL31130536 | 0.90 | KARS1 (0.57) | KARS1PPARDPPARGPPARACXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483149-B1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | YUHAN CORP (KR) | 2021-01-13 | — | — | EP | claimed |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | YUHAN CORPORATION (KR) | 2019-08-20 | — | — | US | claimed |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | YUHAN CORPORATION (KR) | 2019-05-16 | — | — | US | claimed |
| EP-3483149-A1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Yuhan Corporation (KR) | 2019-05-15 | — | — | EP | claimed |
| US-11378572-B2 | Therapeutic agent for immune cell migration-caused disease and method for screening same | ZYMEDI CO., LTD. (KR) | 2022-07-05 | — | — | US | disclosed |
| US-11378572-B2 | Therapeutic agent for immune cell migration-caused disease and method for screening same | ZYMEDI CO., LTD. (KR) | 2022-07-05 | — | — | US | disclosed |
| EP-3483149-B1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | YUHAN CORP (KR) | 2021-01-13 | — | — | EP | disclosed |
| CN-111629752-A | Pharmaceutical composition for preventing or treating cell migration-related diseases comprising, as an active ingredient, an antibody that specifically binds to the N-terminus of lysyl-tRNA synthetase | 医药生命融合研究团 | 2020-09-04 | — | — | CN | disclosed |
| US-20200141923-A1 | THERAPEUTIC AGENT FOR IMMUNE CELL MIGRATION-CAUSED DISEASE AND METHOD FOR SCREENING SAME | ZYMEDI CO., LTD. (KR) | 2020-05-07 | — | — | US | disclosed |
| US-20200141923-A1 | THERAPEUTIC AGENT FOR IMMUNE CELL MIGRATION-CAUSED DISEASE AND METHOD FOR SCREENING SAME | ZYMEDI CO., LTD. (KR) | 2020-05-07 | — | — | US | disclosed |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | YUHAN CORPORATION (KR) | 2019-08-20 | — | — | US | disclosed |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | YUHAN CORPORATION (KR) | 2019-05-16 | — | — | US | disclosed |
| EP-3483149-A1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Yuhan Corporation (KR) | 2019-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11378572-B2 | Therapeutic agent for immune cell migration-caused disease and method for screening same | NFATC1, MIF, MMP8 | KARS1 193/4885LPAR1 799/4885LPAR5 922/4885 |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | ILK, SBDS, BDKRB1 | KARS1 6/4885LPAR1 567/4885LPAR5 670/4885 |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | ILK, SBDS, BDKRB1 | KARS1 6/4885LPAR1 567/4885LPAR5 670/4885 |
| US-20200141923-A1 | THERAPEUTIC AGENT FOR IMMUNE CELL MIGRATION-CAUSED DISEASE AND METHOD FOR SCREENING SAME | NFATC1, MIF, MMP8 | KARS1 193/4885LPAR1 799/4885LPAR5 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.