Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.94 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL1270969 | 0.97 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL29349552 | 0.97 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL2774 | 0.97 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL32661377 | 0.97 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL29822171 | 0.97 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL23202414 | 0.94 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL5714730 | 0.94 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL2590325 | 0.94 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL6381814 | 0.94 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL20969722 | 0.94 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174879-A | Method for preparing 2-chloronicotinaldehyde | 西安凯立新材料股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-110054693-A | The antibody and application thereof of Quetiapine haptens | 詹森药业有限公司 | 2019-07-26 | — | — | CN | claimed |
| CN-109803658-A | Combined therapy comprising the Imidazopyrazines ketone for treating mental disease and/or cognitive disorder | H.隆德贝克有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-104725363-B | Substituted diethylenediamine compound and its application method and purposes | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109142593-A | HPLC-DAD method measures Quetiapine drug concentration in human serum | 沈阳和合医学检验所有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-106243088-B | Substituted diethylenediamine compound and its application method and purposes | 广东东阳光药业有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-109069870-A | Treatment candidate screening system, model and their application for Huntington's disease based on embryonic cell | 洛克菲勒大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108165959-A | Chemical bronze plating liquid | 永星化工(上海)有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-105980858-A | Use of sortilin as biomarker for affective/mood disorders | H.隆德贝克有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-104193613-B | 1,3,5 three (2 carboxy vinyl) benzene and preparation method thereof | NANTONG UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-120208871-A | Quinoline sulfur-containing derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-06-27 | — | — | CN | disclosed |
| CN-111747841-B | Preparation method of 4-formylbenzoic acid and obtained 4-formylbenzoic acid | 北京博诺安科科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-109438210-B | Preparation method of pivalic aldehyde | 陕西理工大学 | 2022-01-07 | — | — | CN | disclosed |
| CN-109438210-B | Preparation method of pivalic aldehyde | 陕西理工大学 | 2022-01-07 | — | — | CN | disclosed |
| US-4045580-A | PHARMACEUTICAL PREPARATION USING 9-(2-HYDROXY-3-AMINO-PROPYL)-9,10-DIHYDRO-9,10-ETHANO-ANTHRACENES AS ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4017542-A | 9-(2-Hydroxy-3-amino-propyl)-9,10-dihydro-9,10-ethano-anthracenes and salts thereof | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |
| US-4011334-A | USE OF SUBSTITUTED FURAN AND THIOPHENE CARBOXALDEHYDES AS HYPOLIPIDEMIC AGENTS | RICHARDSON-MERRELL INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-3954862-A | RHODIUM CATALYZED HYDROGENATION | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3931181-A | BACTERICIDE | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |