Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313452 | 0.85 | KDM4E (0.46) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27450984 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| SCHEMBL8972595 | 0.78 | LMNA (0.42) | ALDH1A1POLBLMNASMN1; SMN2NPC1 | |
| SCHEMBL30540107 | 0.78 | LMNA (0.42) | ALDH1A1POLBLMNASMN1; SMN2NPC1 | |
| SCHEMBL10603635 | 0.78 | POLB (0.46) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| SCHEMBL27807728 | 0.77 | — | — | |
| SCHEMBL4911938 | 0.77 | LMNA (0.49) | ALDH1A1POLBLMNASMN1; SMN2NPC1 | |
| SCHEMBL27599227 | 0.75 | APP (0.34) | ALDH1A1KDM4EPOLBL3MBTL1LMNA | |
| SCHEMBL9723797 | 0.73 | LPAR3 (0.37) | ALDH1A1LMNAMAPT | |
| SCHEMBL4823292 | 0.73 | TSHR (0.36) | ALDH1A1KDM4EPOLBGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448543-B1 | USE OF MORPHOLINE-BASED HINDERED AMINE COMPOUNDS FOR SELECTIVE REMOVAL OF HYDROGEN SULFIDE | BASF SE (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-20190143262-A1 | USE OF MORPHOLINE-BASED HINDERED AMINE COMPOUNDS FOR SELECTIVE REMOVAL OF HYDROGEN SULFIDE | BASF SE (DE) | 2019-05-16 | — | — | US | disclosed |